Tehran University of Medical Sciences
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Gholam Ali Kardar

Contact Information
http://iaari.tums.ac.ir/
Tel: +98 21 66919589 (ext 121)
Fax: +98 21 66428998
Address: Immunology, Asthma and Allergy Research Institute, Children's Medical Center, No. 62, Dr. Gharib St, Keshavarz Blvd.,Tehran 1419
Academic Rank
Professor
School
Medicine
Immunology
Research Center
Immunology, Asthma & Allergy Research Center
About
I work on cancer Immunotherapy and also on genome editing as a strategy for engineering T cells for better and stronger fight against tumor cells. In beside of neoantigens based Adoptive T cell therapy, we have a national project on gene therapy of primary immunodeficiency diseases (PID). Obviously in this line, we have to do cell knock-out, cell engineering, and cell genome editing. I welcome domestic and abroad PI who are willing to collaborate and develop joint projects.
CV last edited on: 2023/29/05

Education

1.

Ph.D


Molecular Genetics , Basic Sciences Department, NIGEB, IRAN, 2010
2.

MSPH


Medical Immunology, School of Public Health, Tehran University of Medical Sciences, IRAN, 2001
3.

B.Sc


Biology (Zoology), Tehran University, IRAN, 1994

Language Skills

1.

Persian


Speaking: Native, Reading: Native, Writing: Native
2.

Mazani


Speaking: Native, Reading: Native, Writing: Native
3.

English


Speaking: Good, Reading: Good, Writing: Good

Awards & Honors

1.

Tasnim Research Award


2016,
2.

Distinctive, National Youth Talent, National Foundation Elite


2007,
3.

National Research Festival on Medical Sciences Award


2003,

Selected as the best M.Sc. thesis in 9th Razi Festival, Iran’s President gave awards.

Experiences

Scientific Position

1.

Associate Professor


Tehran University of Medical Sciences, 2018-2022
2.

Assistant Professor


Tehran University of Medical Sciences, 2011-2017
3.

Professor


Tehran University of Medical Sciences, 2023-Present
4.

Visiting Professor


University of Toronto, Department of Immunology, 2018-2019

Course Teaching

M.Sc

1.

Genetic Engineering


SATiM,M.Sc.
2.

Advanced Cell Culture


SATiM,M.Sc.
3.

Immunopathology: Inflammation & Cancer


IAARI ,M.Sc.

Ph.D

1.

Essential of molecular diagnosis in biotechnology


SATiM,Ph.D.
2.

Vaccines


SATiM,Ph.D.
3.

Advanced Genetic Engineering


SATiM,Ph.D.
4.

Cancer biology and immunotherapy


IAARI,Ph.D.
5.

Molecular Immunology


SATiM,Ph.D.
6.

Clinical Immunology: Gene therapy methods


IAARI ,Ph.D.

Papers

English

1.

Immunotherapy & Gene therapy [selected]


Authors: ----------------------------------------------------------------------------------------

2.

Cobalt Chloride-induced Hypoxia Can Lead SKBR3 and HEK293T Cell Lines toward Epithelial-mesenchymal Transition


[PubMed]
Authors: Sadri M, Delbandi AA, Rashidi N, Kardar GA, Falak R.
Iran J Allergy Asthma Immunol, Year. 2022, Page:449-457,
3.

The Trend of CRISPR-Based Technologies in COVID-19 Disease: Beyond Genome Editing


[PubMed]
Authors: Najafabadi ZY, Fanuel S, Falak R, Kaboli S, Kardar GA.
Molecular biotechnology, Year. 2022, Page:1-16,
4.

FAM72A antagonizes UNG2 to promote mutagenic repair during antibody maturation


[Nature] [PubMed]
Authors: Feng Y, Li C, Stewart JA, Barbulescu P, Desivo NS, Álvarez-Quilón A, Pezo RC, Perera MLW, Chan K, Tong AHY, Mohamad-Ramshan R, Berru M, Nakib D, Li G, Kardar GA, Carlyle JR, Moffat J, Durocher D, Di Noia JM, Bhagwat AS, Martin A.
Nature, No.Online ahead of print, Year. 2021,
5.

Overexpression of bHLH domain of HIF-1 failed to inhibit the HIF-1 transcriptional activity in hypoxia.


[PubMed]
Authors: Sadeghi F, Kardar GA, Bolouri MR, Nasri F, Sadri M, Falak R.
Biological Research, Vol.53, No.1, Year. 2020,
6.

Induction of humoral immune responses and inhibition of metastasis in mice by a VEGF peptide-based vaccine


[PubMed]
Authors: Soltanpour Gharibdousti F, Fazeli Delshad B, Falak R, Shayanfar N, Ganjalikhani Hakemi M, Andalib A, Kardar GA
Iran J Basic Med Sci., Vol.23, No.4, Year. 2020,
7.

A truncated Snail1 transcription factor alters expression of essential EMT markers and suppresses tumor cell migration in a human lung cancer cell line


[PubMed]
Authors: Davoodzadeh Gholami M, Falak R, Heydari S, Khoshmirsafa M, Zarnani AH, Safari E, Tajik N, Kardar GA
Recent Patents on Anti-Cancer Drug Discovery, Vol.14, No.2, Year. 2019, Page:158-169,
8.

Effects of Influenza Derived Peptide on CD8 T Cell Responses to MHC Class I-Restricted Human Telomerase Reverse Transcriptase (hTERT)- Derived Peptide


[PubMed]
Authors: Gholizadeh Navashenaq J, Gowhari Shabgah A, Alsadat Hashemi E, Seyedzadeh MH, Shokri F, Razavi SA, Kardar GA
International Journal of Peptide Research and Therapeutics, Vol.https://doi.org/10.1007/s10989-0, Year. 2018,
9.

CEA Plasmid as Therapeutic DNA Vaccination against Colorectal Cancer.


[PubMed]
Authors: Veisi Malekshahi Z, Hashemi Goradel N, Shakouri Khomartash M, Maleksabet A, Kadkhodazadeh M, Kardar GA, Negahdari B
Iranian Journal of Immunology, Vol.16, No.3, Year. 2019, Page:235-245,
10.

Exhaustion of T lymphocytes in the tumor microenvironment: Significance and effective mechanisms


Authors: Davoodzadeh Gholami M, Kardar GA, Saeedi Y, Heydari S, Garssen J, Falak R
Cellular Immunology, Vol. [Epub ahead of print], Year. 2017,
11.

Effects of Viral Peptide Presentation on CD4+ T Cell Responses to MHC Class II-Restricted Tumor Peptides


Authors: Gowhari Shabgah A, Gholizadeh Navashenaq J, Seyedzadeh H, Moghadasi M, Shokri F, Razavi A, and Kardar GA
Int J Cancer Manag, Vol.10, No.6, Year. 2017, Page:e8174,
12.

Allergy vaccine & Immunotherapy [selected]


Authors: ----------------------------------------------------------------------------------------

13.

A Comprehensive Overview of Allergen-specific Immunotherapy Types, Recombinant and Natural Extract Allergens in the Diagnosis and Treatment of Allergies


[PubMed]
Authors: Asoudeh Moghanloo S, Forouzanfar M, Jafarinia M, Fazlollahi MR, Kardar GA.
Iranian Journal of Allergy Asthma & Immunoogy, Year. 2022, Page:494-511,
14.

Design and evaluation of a hypoallergenic peptide-based vaccine for Salsola kali allergy


Authors: Tabesh S, Fanuel S, Fazlollahi MR, Yekaninejad MS, Kardar GA, Razavi SA
Int Immunopharmacol, Vol.66, Year. 2019, Page:62-68,
15.

Novel report of the phytochemical composition from Fraxinus excelsior pollen grains


Authors: Shoushtari MS, Majd A., Nejadsattari T, Moin M, Kardar GA
Journal of applied botany and food quality , Vol.91, Year. 2018, Page:310,
16.

Computational Analysis of Specific IgE epitopes Responsible for Allergy to Fish


Authors: Mohamadi M, Falak R, Zolfaghari Emameh R, June Maleki S, Kardar GA
Current Immunology Reviews, Vol.10.2174/157339551466618062212175, Year. 2018,
17.

Construction of a recombinant B-cell epitope vaccine based on a Der p 1-derived hypoallergen: a bioinformatics approach


Authors: Fanuel S, Tabesh S, Mokhtarian K, Sadroddiny E, Fazlollahi MR, Pourpak Z, Falak R, Kardar GA
Immunotherapy, Vol.10, No.7, Year. 2018, Page:537-553,
18.

Decorating and loading ghosts with allergens for allergen immunotherapy


Authors: Fanuel S, Tabesh S, Rajani HF, Heidari S, Sadroddiny E, Kardar GA
Human vaccines & Immunotherapeutic, Vol.13, No.10, Year. 2017, Page:2428-2433,
19.

Analysis of predicted B and T-cell epitopes in Der p 23, allergen from Dermatophagoides pteronyssinus


Authors: Fanuel S, Tabesh S, Sadroddiny E, Kardar GA
Bioinfirmation, Vol.13, No.9, Year. 2017,
20.

Peptide-based Vaccines Derived from FcεRI Beta Subunit Can Reduce Allergic Response in Mice Model


Authors: Zare A, Pourfathollah AA, Pourpak Z, Szebeni J, Ghaffari SMR, Kardar GA.
Iranian Journal of Allergy Asthma and Immunology, Vol.16, No.4, Year. 2017, Page:289-297,
21.

PubMed full list


[PubMed Articles list]
Authors:

Editorial Board & Reviewing Activities

1.

Nutrition and Cancer


Manuscript Peer Reviewer (International Journal),
2.

Clinical and Translational Oncology


Manuscript Peer Reviewer (International Journal),
3.

International Journal of Immunogenetics


Manuscript Peer Reviewer (International Journal),
4.

Immunobiology


Manuscript Peer Reviewer (International Journal),
5.

Avicenna Journal of Medical Biotechnology


Manuscript Peer Reviewer (National Journal),
6.

Iranian Journal of Biotechnology


Manuscript Peer Reviewer (National Journal),
7.

Iranian Journal of Allergy, Asthma and Immunology


Manuscript Peer Reviewer (National Journal),

Skills

1.

Methods in ELISA, Electrophoresis & Blotting techniques


2.

Cell culture, Banking & Transformation


3.

Production, Purification & characterization methods of Monoclonal Antibodie


4.

Protein engineering & Bioinformatics


5.

Molecular biology techniques & Molecular Cloning


6.

EndNote & SPSS


Memberships

1.

Member of National Foundation Elite


Activity Type:Member
2007-present
2.

Iranian Society for Immunology & Allergy


Activity Type:Member
2002-Present
3.

Iranian Biotechnology Society


Activity Type:Member
2005-present

Research Interests

1. Cancer Immunotherapy and vaccine design
2. Gene Therapy
3. Allergy vaccine & Immunotherapy

 

 

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